Breathing and Exchange of Gases
NCERT Class 11 Biology Chapter 14
Breathing and Exchange of Gases for Class 11 Biology and NEET: human respiratory system, mechanism of breathing, gas exchange and transport, and disorders.
6 topics Updated 8 Nov 2026
In the syllabus: NEET Class 11 syllabus
With your textbook
NCERT Biology (Class 11), Chapter 14 “Breathing and Exchange of Gases”, reprint 2026-27.
Open the official NCERT chapter (PDF, 2.1 MB, ncert.nic.in) (opens in a new tab)
Checked on 19 Oct 2026.
Learn in this order
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Respiratory organs and the human respiratory system
Organs in animals, the airway to the alveoli with a labelled diagram, and breathing vs respiration.
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Mechanism of breathing and lung volumes
Inspiration vs expiration, the diaphragm and intercostals, respiratory volumes and capacities, with examples.
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Exchange of gases and partial pressures
Diffusion at the alveoli and tissues, pO and pCO from NCERT Table 14.1, and the three-layer diffusion membrane.
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Transport of oxygen and carbon dioxide
Oxyhaemoglobin, the oxygen dissociation curve and its shifts, the Bohr effect, bicarbonate, carbonic anhydrase.
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Regulation of respiration
Medulla, pons, CO and H sensing, and the important response to low arterial oxygen.
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Disorders of the respiratory system
Asthma vs emphysema, occupational disorders such as silicosis, and what each one damages.
Key formulas in this chapter
Respiratory organs
- airway: nostrils → nasal chamber → pharynx → larynx → trachea → bronchi → bronchioles → alveoli
- conducting part: nostrils to terminal bronchioles; exchange part: alveolated respiratory region
- NCERT: trachea divides at the 5th thoracic vertebra
- steps: breathing → alveolar diffusion → transport → tissue diffusion → cellular respiration
Mechanism of breathing
- IC = TV + IRV; EC = TV + ERV
- FRC = ERV + RV
- VC = ERV + TV + IRV
- TLC = VC + RV = RV + ERV + TV + IRV
- TV about 500 mL; 12–16 breaths a minute; 6000–8000 mL a minute
Exchange of gases
- alveoli: pO 104, pCO 40 mm Hg; tissues: pO 40, pCO 45 mm Hg
- deoxygenated blood: pO 40, pCO 45; oxygenated blood: pO 95, pCO 40
- atmospheric air: pO 159, pCO 0.3 mm Hg
- solubility of CO = 20–25 × that of O
- diffusion membrane: squamous epithelium + basement substance + endothelium
Transport of gases
- NCERT O shares: 97 per cent as oxyhaemoglobin, 3 per cent dissolved
- CO: 70 per cent bicarbonate, 20–25 per cent carbamino-haemoglobin, 7 per cent dissolved
- CO + HO ⇌ HCO ⇌ HCO + H (carbonic anhydrase)
- 100 mL blood: delivers about 5 mL O; about 4 mL CO
- up to 4 O per haemoglobin molecule
Regulation of respiration
- respiratory rhythm centre: medulla (primary control)
- pneumotaxic centre: pons; can shorten inspiration
- chemosensitive area: beside the rhythm centre; senses CO and H
- aortic arch and carotid artery receptors: sense CO and H
- oxygen: small influence near normal pO; strong peripheral drive when arterial pO falls substantially
Disorders of respiratory system
- asthma: inflamed bronchi and bronchioles; wheezing
- emphysema: damaged alveolar walls; less respiratory surface; smoking
- dust-related occupational fibrosis: hazardous dust → inflammation → scarring
- protection: control dust at source; use appropriate fitted respirators when required
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